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4 edition of Tracheobronchial smooth muscle cells as a potential source of secretory phospholipase A2 found in the catalog.

Tracheobronchial smooth muscle cells as a potential source of secretory phospholipase A2

Addic A. Rillon

Tracheobronchial smooth muscle cells as a potential source of secretory phospholipase A2

by Addic A. Rillon

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  • 25 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

Thesis (M.Sc.) -- University of Toronto, 2000.

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches : negative. --
ID Numbers
Open LibraryOL19326963M
ISBN 100612497690
OCLC/WorldCa51736000

Lineage-tracking strategies. (A) For investigating the origin of a set of cells, A, several different, mutually exclusive, candidate populations can be successively labelled with a tracking marker, and it can be determined if labelled cells turn of among A the example shown, the phenotypic marker used to define A is a red membrane stain and the candidate population C is labelled with Furchgott RF, Zawdazki JV () The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature – PubMed Google Scholar

Endocrine cells in the small intestine Targets smooth muscle of antrum and duodenum Stimulates a contraction pattern in the distal stomach and small intestine between meals known as the migrating motor complex (MMC). Acts on other neurons within the ENS to begin the MMC ://    Phenotypic switching. Several studies demonstrated that the vascular smooth muscle cells have phenotypes that differ in the media and atherosclerotic lesions, and that phenotypic switching of SMCs plays a central role in atherosclerosis according to Ross's hypothesis [3, 4].It has been proposed that before migration from the media into the intima, a transition of the SMCs phenotype is

Quercetin is the great representative of polyphenols, flavonoids subgroup, flavonols. Its main natural sources in foods are vegetables such as onions, the most studied quercetin containing foods, and broccoli; fruits (apples, berry crops, and grapes); some herbs; tea; and wine. Quercetin is known for its antioxidant activity in radical scavenging and anti-allergic properties characterized by Sejersen T, Betsholtz C, Sjölund M, Heldin C-H, Westermark B, Thyberg J () Rat skeletal myoblasts and arterial smooth muscle cells express the gene for the A chain but not the gene for the B chain (c-sis) of platelet-derived growth factor (PDGF) and produce a


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Tracheobronchial smooth muscle cells as a potential source of secretory phospholipase A2 by Addic A. Rillon Download PDF EPUB FB2

Abstract Addic A. Brillon, lnstitute of Medical Science, University of Toronto, June Mesenchymal cells have been show to synthesize and secrete sPLA, upon stimulation of two However, upon stimulation, sPLA 2 -IIA is also secreted by endothelial, hepatic, renal and smooth muscle cells [30][31][32][33] [34] [35][36][37], in addition to macrophages, mast cells, platelets Judith A.

St George, in Comparative Biology of the Normal Lung (Second Edition), Abstract. The secretory cells of the tracheobronchial epithelium and submucosal glands collectively produce the mucous blanket of the conducting airways.

There is, however, wide variation from species to species in the type of secretory cells at a given airway level, the numbers of secretory cells present Graham R. Bayly, in Clinical Biochemistry: Metabolic and Clinical Aspects (Third Edition), Phospholipase A2.

Phospholipase A2 (PLA2) is one of a family of phospholipases, enzymes that hydrolyse phospholipids. It exists in five forms. Three are found within cells.

Two are secreted, one of which, lipoprotein-associated PLA2 (LpPLA2) is also known as platelet activating factor acetyl Abstract. Secretory cells and tissues are concerned with the accumulation of metabolism by products which are not used as reserve substances. Most secretory cells are specialized cells derived from elements belonging to other tissues, mainly epidermis or parenchymatous :// Hideki Kishimura, in Advances in Food and Nutrition Research, Abstract.

Industrial phospholipase A2 (PLA2) mainly produced from porcine pancreas is used for production of lysolecithin which is well known as an excellent natural emulsifier for food, cosmetic, and pharmaceutical industries.

Since the outbreak of bovine spongiform encephalopathy (BSE) or religious tradition, it is hoped Human tracheobronchial epithelial (TBE) basal cells (BCs) function as progenitors in normal tissue.

However, mechanistic studies are typically performed in vitro and frequently use BCs recovered from patients who die of nonrespiratory disease. It is not known whether the cadaveric epithelium (1) is undergoing homeostatic remodeling and/or repair, or (2) yields BC clones that represent   To elucidate the effects of tumor necrosis factor-α (TNF-α) on tracheal smooth muscle contraction, we simultaneously measured isometric tension and intracellular Ca 2+ ([Ca 2+] i) in fura 2-loaded muscle muscle force generation was evaluated in a high potassium (K +; – mM) solution and with acetylcholine (3 nM–10 μM).TNF-α (1– ng/ml) did not directly Therefore, in this review, we will discuss here how smooth muscle cells contribute or regulate the inflammatory reaction in the progression of atherosclerosis, especially in the context of the activation of various membrane receptors, and how they may regulate vascular inflammation.

[BMB   The trachea, bronchi and bronchioles form the tracheobronchial tree – a system of airways that allow passage of air into the lungs, where gas exchange airways are located in the neck and thorax.

In this article we will look at the anatomical position, structure and neurovascular supply of the airways; as well as considering their clinical :// tracheobronchial的中文意思:adj.【解剖学】气管支气管的。 ,查阅tracheobronchial The functions of the secretory barrier of the tracheobronchial tree are physical, chemical, immunological, and Abstract.

Airway smooth muscle (ASM) cell complexity is becoming increasingly apparent. Initially considered to be merely a contractile element, it is now known that smooth muscle cells actively regulate their function and microenvironment by producing a range of cytokines and low molecular weight products in addition to extracellular :// Clara cells are non-ciliated secretory epithelial cells lining the pulmonary airways, distinct from mucous and serous secretory cells in morphology and secretory products.

Among these, the Clara cell protein (CC16) plays an immunomodulatory activity, it can inhibit phospholipase A2 activity, while inflammatory cytokines like TNF-α can modulate Request PDF | On Jan 1,Qihan Dong and others published Phospholipase A2 | Find, read and cite all the research you need on ResearchGate Abstract.

The excitatory innervation of bovine tracheal smooth muscle has been studied with the sucrose-gap apparatus. Single 2 ms electrical stimuli applied to the whole tissue excited intrinsic nerves, and produced a small transient depolarization of the smooth muscle, the excitatory junction potential Secretory phospholipase A2 group IIa (sPLA2-IIa) is found at high levels in activated inflammatory cells, such as activated macrophages, and some cancers.

sPLA2-IIa, an NF-κB target gene (19,20 The epithelium consists mainly of ciliated cells and of dark cytoplasmic non-ciliated cells that sometimes contain secretory granules.

Any 'respiratory tract fluid' secreted into the ferret trachea is probably mainly glandular in origin. The epithelium contains neutrophils and a few mast cells and :// The cells generating the extracellular matrix of these regions are smooth muscle cells, and possible macrophages [20,36].

Secretory phospholipase A2 (sPLA2) enzyme activity is a potential Download Citation | Physiology and pathology of tracheobronchial glands | The tracheobronchial glands, composed of mucous and serous secretory cells, provide a mucin-rich, antimicrobial-rich Abstract.

Activity in motor nerves to airway smooth muscle can be influenced by a very large number of reflex inputs; in this respect, the control of tracheobronchial smooth muscle tone resembles other motor components of the autonomic nervous ://.

The percentage of ciliated, secretory, and basal-like cells was 24 ± 2%, 11 ± 1%, 29 ± 1%, respectively, while the remaining 36% were difficult to type. In one subject in whom brushing was performed on three occasions over a 7-wk period, the percentage of each of the three subtypes was similar across ://the C-shaped cartilaginous rings.

The cartilaginous rings are replaced by smooth muscle cells before the bronchi enter into the lung. The lining epithelium of tra-cheobronchial tree gradually changes into simple cuboidal epithelium that lacks goblet cells.

However, the division of the tracheobronchial tree is similar to other mammalian ://The cartilaginous rings are replaced by smooth muscle cells before the bronchi enter into the lung. The lining epithelium of tracheobronchial tree gradually changes into simple cuboidal epithelium that lacks goblet cells.

However, the division of the tracheobronchial tree is similar to other mammalian ://